Rejuran is a cutting-edge, non-hyaluronic acid injectable that launched in Australia in 2023, designed to rejuvenate the skin from within. Powered by polynucleotide DNA, it works through biostimulation – enhancing your body’s own ability to produce collagen for a firmer, smoother, and more radiant complexion. Book a consultation at our Brisbane clinics today!
Key Points
- Stimulates collagen production to repair and rejuvenate skin natural
- Ideal for fine lines, wrinkles, enlarged pores, and acne scars
- Can be used on the face, under-eyes, neck, décolletage, and hand
- Latest polynucleotide-based bioremodulator available in Australia
- Improves skin firmness, elasticity, and hydration without adding volume
- Best results seen after 2-4 treatments, with peak effects at 3 months
Rejuran; at a glance
Our results speak for themselves

Before
After

Early remodelling of acne scars with Rejuran PN injections. B+A after one session. Ideally 2-4 sessions, spaced 4-8 weeks apart.
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Before
After

Subtle by definite, Rejuran PN (Polynucleotide), under eyes, one session, cannula delivery.
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FAQs
What is Rejuran?
Rejuran is a bio-stimulating injectable that harnesses purified polynucleotide (PN) DNA from salmon to repair and rejuvenate the skin. While its source may sound surprising, this powerful treatment has been safely used in Korea and Singapore for nearly a decade, enhancing collagen production, elasticity, and overall skin health.
Rejuran injections support cellular remodeling by:
- Stimulating collagen production
- Slowing the aging process
- Improving fine lines, wrinkles, pores, and skin texture
- Enhancing skin hydration (though Profhilo excels in this area)
- Reducing the appearance of acne scars
When will I see results from Rejuran?
Initial improvements can appear within the first two weeks, but full collagen remodeling takes 3-6 months.
For optimal results, a series of 2-4 sessions spaced 3-6 weeks apart is recommended.
How many treatments will I need?
Most patients see the best results with 2-4 rejuran sessions spaced 3-6 weeks apart. For deeper wrinkles, sun damage, or skin laxity, a fourth session may be beneficial. To maintain collagen stimulation, 1-2 yearly treatments are recommended.
How long does treatment take & is it painful?
The procedure itself takes 10-15 minutes, with a 30-minute numbing gel application beforehand to minimize discomfort.
What is the recovery time after Rejuran injections?
Recovery typically takes 1-2 days. The small injection blebs from Rejuran usually subside within 12-36 hours.
What can I expect before, during and after treatment?
Before your treatment, you’ll have a consultation with one of our clinicians at our Brisbane clinic (*complimentary nurse consultation). They’ll assess your skin and discuss your goals to ensure Rejuran is the right choice for you.
To minimize discomfort, a numbing gel will be applied to the treatment area for 30 minutes before the procedure. Once you’re ready, the treatment takes just 10-20 minutes, depending on the area. You may feel slight tingling, but the numbing gel makes the process well tolerated.
There’s minimal downtime, so you can return to your normal activities right away. As Rejuran stimulates collagen and skin repair, visible improvements typically begin within a few weeks. Peak results are seen at around 3 months, with smoother skin, fewer fine lines, and improved firmness.
To maintain optimal results, a second session is recommended after one month, helping to sustain collagen production for long-lasting skin rejuvenation.
*Fee redeemable on treatment only; initial $99 applies. This fee is taken for nurse’s time if treatment is not booked.
Where can Rejuran be used?
Rejuran can be used on various areas of the face and body, including:
- The face (for overall skin rejuvenation, wrinkles, and fine lines)
- Under the eyes (for dark circles and skin texture)
- Neck and décolletage (to improve skin quality)
- Hands (for skin hydration and smoothing)
- Other areas with concerns such as acne scars or skin laxity
How Does Rejuran Help Acne Scars?
Rejuran improves acne scars by stimulating collagen production and enhancing skin regeneration. The polynucleotides promote tissue repair, helping to smooth depressed scars and improve overall skin texture. Rejuran S, a thicker formulation, is particularly effective for atrophic (indented) scars, working to remodel damaged skin over time.
What Can Rejuran Do for Under Eyes?
Rejuran i, a specially formulated version for delicate skin, can improve under-eye concerns by:
- Reducing fine lines and crepey texture
- Improving skin elasticity and firmness
- Brightening dark circles by enhancing circulation and skin repair
- Hydrating and strengthening thin under-eye skin
With minimal downtime, Rejuran I offers a natural, refreshed look over time.
Rejuran is a groundbreaking treatment that harnesses the power of polynucleotide DNA to rejuvenate and restore your skin, stimulating collagen for a visibly smoother, firmer, and more radiant complexion.
How is Rejuran different from hyaluronic acid volumisers?
Rejuran stimulates collagen production for long-term skin rejuvenation, while volumisers add instant volume and smooth wrinkles.
Rejuran improves skin quality over time, whereas fillers provide immediate, temporary results.
Will Rejuran make my skin firmer and more lifted?
The goal is to stimulate collagen production for firmer, more lifted skin, but results can vary. Rejuran keeps collagen-producing cells active, leading to improvements in
- wrinkles, fine lines
- dry skin, enlarged pores
- uneven tone
- sagging skin
- acne scars
Some patients may experience more noticeable results than others.
What age can I get Rejuran?
While biostimulators are safe for adults of any age, they are most effective from the late 20s onward. Since collagen levels start declining by 1% per year after 20, mild biostimulation in the mid to late 20s can help maintain skin quality and slow aging.
Can Rejuran be combined with other treatments?
- Rejuran + Profhilo: Profhilo deeply hydrates, while Rejuran stimulates collagen for enhanced skin quality.
- Rejuran + Dermal Fillers: Rejuran boosts collagen, while fillers restore lost volume.
- Rejuran + Lasers: This synergy enhances collagen production, with a downtime of 3-4 days.